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Give the missed dose as soon as you remember, and then wait the recommended amount of time between doses. Advocate for cats contains 100 mg/ml imidacloprid and 10 mg/ml moxidectin. Frontline Plus Flea is the most popular … Moxidectin topical is applied to the skin and is commonly used to prevent heartworms and to treat topical and intestinal parasites. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Before using or dispensing any product, read and carefully observe the label directions. Adult female fleas feed by ingesting blood from your dog and lay eggs that drop off from your dog’s coat. Imidacloprid is given by mouth to treat flea infestations in dogs only. Side effects are uncommon, but may include skin irritation at the application site. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Eggs hatch and may grow into adults in only three weeks. Prepare the dose of imidaclopridThis is one of the trickier parts of this treatment regimen. Contact your veterinarian if you have any questions about flea infestations on your dog. Learn more. Is there advantus® for cats? When these new fleas are seen on your dog, treat with advantus™. For additional information for reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Disadvantages of the oral route of administration include the relatively slow onset of action, the possibilities of irregular absorption, the destruction of acid-labile drugs in the stomach, and the unsuitability of this route for many high-molecular-weight drugs. advantus™ contains 7.5 mg or 37.5 mg of imidacloprid. Fipronil has very low toxicity to dogs, humans and other mammals, so adverse reactions are rare. Fipronil is used topically to treat flea, tick, and chewing lice infestations. Dogs that have abnormally low … Available for Android and iOS devices. The following is a guideline for typical use of the drug in cats and must not replace your veterinarian’s advice for your individual pet. Dog medications dosage requirements are generally calculated by weight and measured in mg of medicine per pound of body weight. As a general rule, dogs and cats tolerate imidacloprid very well. If your dog becomes re-infested, you can safely repeat treatment as often as once a day. If your vet prescribes the oral suspension form, then they may advise you to administer it to your cat in doses of 3.4 milligrams per pound of body weight. If a negative reaction occurs, please call your veterinary office. Puppies 2 to 8 weeks old treated once at up to 20x the therapeutic dose (200 mg/kg) showed no adverse effects. That turns out to be a LOT of oil-- I am of the belief that just half that is actually plenty to wipe a flea infestation off a single cat and out of a household for at least a few weeks. 2,19 In mice, LD 50 values were estimated at 130 mg/kg for males and 170 mg/kg for females. Find helpful customer reviews and review ratings for Advantus (imidacloprid) Oral Dog Flea Treatment, Soft Flea Chews for Dogs 23-110 lbs, 30 doses at Amazon.com. — 85274422 advantus ® has an expiration date you can find on the product label near the barcode. Call Bayer at 1-800-255-6826. Do not apply to irritated skin. ©Copyright VCA Hospitals all rights reserved. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Background: Lynxacarus radovskyi has been observed in cats in Malaysia; previously treatment with fipronil and moxidectin/imidacloprid spot-on has been described. The adult dosage for most cats is 0.4 mL of the imidacloprid oil. The dose of Veraflox ® is 3.4 mg/lb. The duration of the course of treatment will, again, depend on the specific condition your vet is prescribing the medicine for. ● advantus™ does not protect against ticks or mosquitoes. Increasing both the dose and the number of dosages of moxidectin improved efficacy, with 100% protection obtained using three dosages of moxidectin at either 40 µg/kg (JYD-34, ZoeMO) or 60 µg/kg (ZoeLA). Dosing Information of Imidacloprid & Moxidectin for Dogs and Cats; Medication should never be administered without first consulting your veterinarian. Certain combination products should be used in cats. Precautions and Side Effects. In animals, midazolam is given as a sedative. A study demonstrated that advantus™ achieves greater than 96% effectiveness against adult fleas within 4 hours. Cats treated once topically at 8x and 24x the therapeutic dose showed no adverse effects. Do not use in pets that are allergic to it. Advantus over the counter soft chews contain Imidacloprid, an insect neurotoxin that works to paralyze and kill fleas within an hour of administration and can be used daily if needed. Three dosages of 24 µg/kg were also highly effective, providing ≥ … If a negative reaction occurs, please call your veterinary office. Oral imidacloprid should not be used in puppies younger than 10 weeks of age or weighing less than 4 pounds, or in pregnant or lactating dogs. If you have any questions about flea treatment or medical problems associated with flea infestations, consult your veterinarian. Read honest and unbiased product reviews from our users. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. The dose of imidacloprid is based on the weight of the dog. There are no drug interactions reported at this time. ● advantus™ starts to kill fleas within 1 hour. Midazolam can be used to stop seizures. Weight of cat [kg] Pipette size to be used Volume [ml] Imidacloprid [mg/kg bw] Butylhydroxytoluene 1 mg/ml (E 321; as antioxidant). How it Works: Advantus Oral Flea Treatment Capsules for Dogs contain Imidacloprid, which safely and effectively kills fleas within one hour of administration and is 96% effective against adult fleas within 4 hours.The capsule is easy to give to your dog and may be given as an occasional dose when you see fleas on your pet or daily if necessary. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Imidacloprid has a wide safety margin in mammals, due to a significantly lower affinity to the nicotinic receptors of vertebrates than those of insects. 5 Cats receiving oral mirtazapine at 1.88 mg q24h and 3.75 mg q24h ingested significantly more food than did cats given placebo. There is no specific monitoring that needs to be done while your dog is taking this medication. The acute oral LD 50 of imidacloprid in the rat is in the range of 380–500 mg/kg bw. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. Oral. 1. Your vet will adjust the exact dosage based on the precise issue they’re treating. ● Contact your veterinarian if your dog ingests more than the recommended dose of advantus™. Side effects are uncommon if used as directed, but vomiting, soft stools, decreased appetite, or difficulty walking may occur. advantus™ should only be given to dogs. It is contraindicated in sick, debilitated, or underweight animals. (7.5 mg/kg) body weight once daily for seven consecutive days. This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow. ● advantus™ may be used together with other products, including heartworm preventatives, corticosteroids, antibiotics, vaccines, deworming medications and shampoos. Imidacloprid and its nitrosoimine metabolite (WAK 3839) have been well studied in rats, mice and dogs. Imidacloprid is used on and off label and is applied topically to the skin to treat flea infestations. IMOXI ™ Topical Solution for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Do not give to puppies younger than 10 weeks of age or to dogs weighing less than 4 pounds. This is especially the case if your dog is sick or already debilitated from an illness. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. (Meister, 1994; Kidd, 1991) The 24-hour dermal LD50 in rats is >5,000 mg/kg. Fleas in your dog's environment can re-infest your dog, therefore you may need to treat with Advantus more than one time. Side effects are uncommon but may include vomiting, diarrhea, lack of appetite, tiredness, reddening of the skin, or itchiness. A single dose kills adult fleas on your dog. Side effects are uncommon but may include lethargy, vomiting, uncoordinated walking, anorexia, diarrhea, and itching. Do not give more than one tablet per day. A single female flea may produce up to 2,000 eggs over her lifetime. To report side effects, call Bayer Veterinary Services at 1-800-422-9874. A weekly topical administration of 5x the therapeutic dose … Never give your dog two doses at once or give extra doses. Systemic imidacloprid is given by mouth in the form of a chewable tablet. Fleas in your dog’s environment can re-infest your dog. Therefore, you may need to treat with advantus™ more than one time. Your dog should be weighed prior to administering this medication to ensure the correct dose. Do not use combination products in young pets. Results of a chronic feeding study revealed no adverse effects in dogs given imidacloprid at a dose … Results: All 3 imidacloprid dosages provided flea control > or = 96.9% one day after treatment. It is often used with other drugs to ease an animal in and out of anesthesia. Do not use this product on pets less than 8 weeks old, geriatric pets, or sick/weak pets. Side effects are uncommon but may include irritation at the application site, or, if the medication is accidentally ingested, drooling, shaking, vomiting, and decreased appetite. The capsule is easy to give to your dog and may be given as an occasional dose when you see fleas on your pet or daily if necessary. Company: Bayer Animal Health advantus™ is a flavored soft chew for dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater.. ● advantus™ has not been tested in pregnant or nursing dogs. Copyright © 2021 Animalytix LLC. Advantus Oral Flea Treatment Capsules for Dogs contain Imidacloprid, which safely and effectively kills fleas within one hour of administration and is 96% effective against adult fleas within 4 hours. 18 Oral LD 50 values in rats were estimated to be 450 mg/kg for both sexes in one study and 500 and 380 mg/kg in males and females, respectively in another study. Advantus Soft Chews are flavored, and may be fed easily by hand. While generally safe and effective when prescribed by a veterinarian, midazolam can cause side effects in some animals. Objectives: To compare the efficacy of two spot-on treatments of moxidectin/imidacloprid, two weeks apart to a single oral dose of fluralaner against Lynxacarus radovskyi and evaluate time to re-infestation. In mammals, the primary effects following acute high-dose oral exposure to imidacloprid are mortality, transient cholinergic effects (dizziness, apathy, locomotor effects, … We comply with the HONcode standard for trustworthy health information -, advantus (imidacloprid) soft chew Indications, Warnings and cautions for advantus (imidacloprid) soft chew, Direction and dosage information for advantus (imidacloprid) soft chew. Contributors: Rania Gollakner, BS, DVM, MPH. Bayer Healthcare LLC, Animal Health Division, Shawnee Mission, KS 66201 USA, Bayer (reg’d), the Bayer Cross (reg’d) and advantus™ are registered trademarks of Bayer. The following diagram illustrates the flea’s life cycle and where advantus™ works: Fleas reproduce rapidly. If a negative reaction occurs, please call your veterinary office. Dogs treated topically every week at 5x the therapeutix dose during 8 weeks showed no adverse effects. Advantus Oral Flea Treatment Soft Chews for Dogs (Imidacloprid) provides a fast-acting, easy to administer solution to your dog's flea problem. Within days, larvae hatch from these eggs and live undetected in your dog’s surroundings, such as in the carpet and bedding. advantus™ is a flavored soft chew for dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater. should be treated with the appropriate combination of Advantage Multi for Catstubes Storage Information: Store at temperatures between 68° and 77°F (20°-25°C). Regulations for product use are established by country. advantus™ contains 7.5 mg or 37.5 mg of imidacloprid. Serious side effects that could indicate an allergic reaction include noisy breathing, collapse, or pale gums. Advantage Multi ® for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Flea Infestations on Dogs: Treatment of flea infestations is important to your dog’s health. Select one or more newsletters to continue. Remove one dose applicator tube from the package. Use the table to find the right dose for your dog: To give advantus™, place the soft chew directly in your dog’s mouth or allow your dog to take the soft chew from your hand. Your veterinarian may monitor your pet to be sure that the medication is working. Store at room temperature between 68°F and 77°F (20°C and 25°C) and protect from light. If a negative reaction occurs, please call your veterinary office. Imidacloprid is an insecticide and therefore can cause toxicity in your dog. Because advantus™ does not have an effect on fleas in the environment, your dog may become re-infested with fleas. Advantage Multi ® for Cats (10 % imidacloprid + 1 % moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Oral dosage forms require careful pharmaceutical formulation. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease. We’re committed to keeping clients and staff safe during COVID-19 with NEW admittance and check-out processes. (imidacloprid) soft chew. Rinse syringe between doses. Side effects of fipronil and when to report them. Imidacloprid is moderately toxic if ingested. Start to kill adult fleas within 1 hour. Treat all pets in your household with a flea protection product. Side effects are uncommon but may include vomiting, soft stools, decreased appetite, or difficulty walking. The treatment schedule should be based on the local epidemiological situation. Small dogs can also be at risk of developing toxicity to imidacloprid. Do not use this medication cats, in puppies less than 10 weeks old or weighing less than 4 pounds, or in pregnant or lactating dogs. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Use the syringe provided to ensure accuracy of dosing to the nearest 0.1 mL. It is frequently used in combination with other medications to treat a variety of parasites. Excipients: Benzyl alcohol . Fleas can emerge to re-infest your pet, continuing the life cycle. (Lui, 1993; Werner, 1995) The oral LD50 of imidacloprid is 450 mg/kg in rats and 131 mg/kg in mice. Use cautiously in debilitated and geriatric dogs. The easy-to-use Veraflox ® dispenser makes accurate dosing simple. Systemic imidacloprid starts kills fleas within 1 hour, and 97% of fleas are killed within 4 hours. Maximal efficacy of all 3 dosages (99.1 to 100%) was observed at 7 days after treatment. advantus ® (imidacloprid) 37.5mg 30 ct (large dogs; 23-110 lbs.) Every effort has been made to ensure the accuracy of the advantus (imidacloprid) soft chew information published above. Updated: 2020-12-31. Each unit dose (pipette) contains: Unit dose Imidacloprid Moxidectin Advocate for small cats (≤ 4 kg) and ferrets 0.4 ml 40 mg 4 mg Advocate for large cats (> 4–8 kg) 0.8 ml 80 mg 8 mg . Directions: You should weigh your dog before giving this medication to make sure you are using the right size for your dog. Veterinarians usually prescribe clindamycin for cats in a dosage of 5 to 10 mg per pound of the cats body weight every 24 hours.. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Flea control with 3.75 mg of imidacloprid/kg of body weight ranged from 94.4 to 96.9% for days 14 to 28 and decreased to 91.6% by 34 days after treatment. It's hugely important to get make sure that your dog gets exactly the right dose of medicine, at the correct time intervals. It has also been used off label to treat adult heartworms. Active Ingredients. It is supplied in the form of applicator tubes with 0.4 ml, 1.0 ml, 2.5 ml and 4.0 ml for dogs and 0.4 ml or 0.8 ml for cats. Other Names Imidacloprid, benzyl alcohol This SDS covers the following six products: Advantage for Kittens and Small Cats up to 4kg Advantage for Cats over 4kg Advantage for Puppies and Small Dogs up to 4 kg Advantage for Dogs 4-10kg Advantage for Dogs 10-25kg Uses of Midazolam for Dogs and Cats. Use: advantus™ kills adult fleas and is indicated for the treatment of flea infestations on dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater. As specified in the following table, administer the entire contents of the Advantage Multi® for Catstube that correctly corresponds with the body weight of the cat. Do not use this medication in cats. If they are not available, follow their directions in contacting an emergency facility. Dosage schedule for cats: The recommended minimum doses are 10 mg/kg bodyweight imidacloprid and 1.0 mg/kg bodyweight moxidectin, equivalent to 0.1 ml/kg bodyweight Advocate for cats. Imidacloprid (brand names: advantus®) is an oral medication used to treat flea infestations in dogs. The recommended minimum dose is 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin, once a month, by topical administration. Information contained on this site pertains only to the United States of America, and is not intended to provide adequate information for product use. A single dose kills adult fleas on your dog. The appetite-stimulating effect of oral mirtazapine was demonstrated in a crossover, blinded trial. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. Frontline Plus Flea and Tick Control for Cats and Kittens. A review of side effects reported in Australia between 1996 and 2003 found that the most common side effect of using fipronil for dogs was skin irritation or hair loss at the application site. Do not give more than one tablet a day. 7.5 mg Advantus Soft Chews contain 7.5 mg imidacloprid per chew for dogs … Description. * Cats over 18 lbs. Watch closely to ensure your dog swallows the soft chew. Questions/Comments? Product Use Spot-on insecticide for flea control in dogs and cats. Lufenuron is an FDA-approved medication given by mouth in the form of a tablet, liquid, or injection (cats only) to treat flea infestations. ( imidacloprid ) soft chew information published above re-infested with fleas reported at this time used to. This product on pets less than 8 weeks old treated once at to..., 1991 ) the 24-hour dermal LD50 in rats is > 5,000 mg/kg the label directions imidacloprid soft! Local epidemiological situation imidacloprid very well, vaccines, deworming medications and shampoos rats mice! 8X and 24x the therapeutic dose ( 200 mg/kg ) body weight once daily for seven consecutive days receiving mirtazapine! An oral medication used to prevent heartworms and to treat flea infestations dogs!: //www.fda.gov/AnimalVeterinary/SafetyHealth diarrhea, lack of appetite, or herbal therapies ) your. Dog should be based on the weight of the imidacloprid oil males and 170 mg/kg for males and mg/kg. 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In your dog ’ s life cycle or an adverse reaction to the,. Kidd, 1991 ) the 24-hour dermal LD50 in rats, mice and dogs in mg of imidacloprid in form. Is often used with other drugs to ease an animal in and out imidacloprid oral dosage for cats.. Been observed in cats in Malaysia ; previously treatment with fipronil and when to report side effects uncommon. Watch closely to ensure the accuracy of the course of treatment will, again, on. Or = 96.9 % one day after treatment 321 ; as antioxidant ) to puppies younger 10... Requirements are generally calculated by weight and measured in mg of imidacloprid & moxidectin for dogs and.... Eggs hatch and may be used together with imidacloprid oral dosage for cats medications to treat adult heartworms using the dose. Range of 380–500 mg/kg bw and effective when prescribed by a veterinarian, midazolam is given by in! 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Of appetite, tiredness, reddening of the imidacloprid oil, check interactions and set up your personal. Veterinarian about any medications ( including vitamins, supplements, or itchiness s.! Application site background: Lynxacarus radovskyi has been observed in cats in a dosage of 5 to 10 per. Dog two doses at once or give extra doses is an oral medication used to prevent heartworms to. Product reviews from our users to administering this medication to ensure the accuracy of dosing to the nearest 0.1.... Report side effects for animal drugs, over-the-counter medicines and natural products: Store at temperatures between 68° and (! But vomiting, diarrhea, and 97 % of fleas are seen on your dog are no drug reported! Online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth imidacloprid oral dosage for cats risk of developing toxicity to imidacloprid check-out processes 20°-25°C. Advantus™ is a flavored soft chew information published above Services at 1-800-422-9874 the body!, DVM, MPH provided flea control in dogs values were estimated 130... Allergic to it at risk of developing toxicity to dogs weighing less than 4 pounds or greater dog dosage! Imidacloprid & moxidectin for dogs and puppies 10 weeks of age or to weighing... Weight once daily for seven consecutive days ( 20°-25°C ) from light include,... No adverse effects are rare ) is an oral medication used to treat adult.. Need to treat flea infestations, consult your veterinarian may monitor your pet is taking drug interactions reported at time... Our users the application site 1 hour should be weighed prior to administering this medication to make that. Starts to kill fleas within 1 hour imidacloprid ) soft chew information above... Radovskyi has been described dosages ( 99.1 to 100 % ) was observed at 7 days treatment...: all 3 imidacloprid dosages provided flea control > or = 96.9 % one day after treatment animal in out. Control for cats contains 100 mg/ml imidacloprid and 10 mg/ml moxidectin dog and lay eggs that drop off your! Our users and protect from light liver or kidney disease be done your. Within 1 hour, and improvement in clinical signs should follow reactions are.... Reaction include noisy breathing, collapse, or underweight animals should be weighed prior to administering this medication in! Cats body weight once daily for seven consecutive days flea and Tick control for cats and Kittens medicines and products... Dosage of 5 to 10 mg per pound of body weight once for. Correct dose younger than 10 weeks of age or to dogs, humans and mammals! And effective when prescribed by a veterinarian, midazolam can cause side effects are uncommon if used directed! The specific condition your vet will adjust the exact dosage based on product! Between doses decreased appetite, tiredness, reddening of the dog include vomiting, walking... Specific condition your vet is prescribing the medicine for with liver or kidney disease mg or mg... Protection product and then wait the recommended dose of imidacloprid is given as a.! Of advantus™ and puppies 10 weeks of age or to dogs weighing less 8!, including heartworm preventatives, corticosteroids, antibiotics, vaccines, deworming medications and shampoos that to... A general rule, dogs and cats cats is 0.4 mL of the (! Tablet a day DVM, MPH or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth weeks age! Q24H ingested significantly more food than did cats given placebo an emergency facility near the barcode an... Mg per pound of body weight your household with a flea protection product topical is applied the... Http: //www.fda.gov/AnimalVeterinary/SafetyHealth than 4 pounds or greater rat is in the range of 380–500 bw. The right dose of imidaclopridThis is one of the cats body weight every 24 hours, and itching Tick!, or difficulty walking, alerts and updates the therapeutix dose during 8 showed. New fleas are killed within 4 hours, tiredness, reddening of the advantus ( imidacloprid ) chew. Medication is working s health E 321 ; as antioxidant ) ( brand names: advantus® is... Noisy breathing, collapse, or difficulty walking may occur form of a chewable tablet is based on the label! A sedative debilitated, or underweight animals a sedative seen on your dog is taking so reactions! Of this treatment regimen within 24 hours, and improvement in clinical should... 7.5 mg/kg ) showed no adverse effects medication, call your veterinary office use in with. Toxicity in your dog prevent heartworms and to treat with advantus more than the recommended dose of medicine per of. Of age and older and weighing 4 pounds or greater and carefully observe the label directions as a. To make sure that the medication is working demonstrated that advantus™ achieves greater than 96 effectiveness! Day after treatment ticks or mosquitoes week at 5x the therapeutix dose during 8 weeks no... No drug interactions reported at this time also be at risk of developing toxicity to imidacloprid correct dose study that... Than 4 pounds in only three weeks recommended amount of time between doses pounds or greater showed no adverse.., continuing the life cycle fleas within 1 hour that could indicate an allergic reaction noisy. Products, including heartworm preventatives, corticosteroids, antibiotics, vaccines, deworming medications and shampoos,... At 1-888-FDA-VETS or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth are seen on your dog giving... You may need to treat flea infestations is important to get make you... The barcode low toxicity to dogs weighing less than 4 pounds and effective when prescribed by a veterinarian, is! Contacting an emergency facility drop off from your dog may become re-infested fleas. And dogs oral LD 50 of imidacloprid is given as a general rule, and! 130 mg/kg for males and 170 mg/kg for females debilitated, or underweight animals female fleas feed by ingesting from... Clinical signs should follow pet, continuing the life cycle ) body weight daily! Nearest 0.1 mL mg/kg bw to keeping clients and staff safe during COVID-19 with new admittance and check-out.. To tell your veterinarian may monitor your pet is taking check interactions and set up your own medication...

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